Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 7/20 | 0.50 |
| ▸ | PDE4A | P27815 | 6/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282312 | 0.86 | FBP1 (0.48) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25546002 | 0.77 | FBP1 (0.48) | BRAFNPC1RAB9ALMNAPOLB | |
| SCHEMBL23782557 | 0.74 | FBP1 (0.44) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23793002 | 0.74 | FBP1 (0.44) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30173814 | 0.74 | FBP1 (0.44) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23782509 | 0.73 | ALDH1A1 (0.51) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25545932 | 0.73 | FBP1 (0.44) | LMNAFBP1KDM4EALDH1A1MAPT | |
| SCHEMBL18282265 | 0.71 | KDM4E (0.37) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25546030 | 0.71 | FBP1 (0.42) | NPC1LMNAPOLBFBP1KDM4E | |
| SCHEMBL18282064 | 0.70 | LMNA (0.42) | BRAFPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12150934-B2 | Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases | BANTAM PHARMACEUTICAL, LLC (US) | 2024-11-26 | — | — | US | disclosed |
| US-20200069656-A1 | Methods of Using Substituted Pyrazole and Pyrazole Compounds and for Treatment of Hyperproliferative Diseases | BANTAM PHARMACEUTICAL, LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069656-A1 | Methods of Using Substituted Pyrazole and Pyrazole Compounds and for Treatment of Hyperproliferative Diseases | KRAS, TP53, CCNA1 | BRAF 64/4885PDE4A 3502/4885PDE4B 3294/4885 |
| US-12150934-B2 | Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases | KRAS, TP53, CCNA1 | BRAF 64/4885PDE4A 3502/4885PDE4B 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.