Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.48 |
| ▸ | BRAF | P15056 | 7/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | HCK | P08631 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.38 |
| ▸ | PRKDC | P78527 | 3/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282312 | 0.87 | FBP1 (0.48) | FBP1BRAFABL1SRCNPC1 | |
| SCHEMBL25545932 | 0.82 | FBP1 (0.44) | FBP1LMNATRPV1 | |
| SCHEMBL25179836 | 0.81 | BRAF (0.43) | FBP1BRAFPIK3CDABL1EGFR | |
| SCHEMBL25546346 | 0.81 | FBP1 (0.48) | FBP1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25546030 | 0.80 | FBP1 (0.42) | FBP1NPC1LMNAPOLBTRPV1 | |
| SCHEMBL25545941 | 0.77 | LMNA (0.48) | FBP1NPC1LMNAPOLBRAB9A | |
| SCHEMBL21772246 | 0.77 | BRAF (0.50) | FBP1BRAFNPC1LMNAPOLB | |
| SCHEMBL23792496 | 0.77 | FBP1 (0.44) | FBP1BRAFNPC1LMNAPOLB | |
| SCHEMBL25183737 | 0.77 | FBP1 (0.45) | FBP1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25546325 | 0.75 | S1PR1 (0.50) | FBP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103368-A | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | FBP1 735/4885BRAF 778/4885PIK3CD 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.