Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 2/20 | 0.67 |
| ▸ | CASP4 | P49662 | 2/20 | 0.67 |
| ▸ | CASP7 | P55210 | 2/20 | 0.67 |
| ▸ | CASP9 | P55211 | 2/20 | 0.67 |
| ▸ | CASP6 | P55212 | 2/20 | 0.67 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.67 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 3/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651922 | 0.88 | CASP3 (0.67) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL11570788 | 0.86 | CASP3 (0.63) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL4625604 | 0.85 | CASP3 (0.67) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL9393227 | 0.85 | ALOX5 (0.55) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL19032878 | 0.85 | CASP3 (0.62) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL21774745 | 0.82 | CASP1 (0.62) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL26621576 | 0.81 | CASP3 (0.62) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL4625557 | 0.81 | CASP3 (0.62) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL1217303 | 0.81 | CASP3 (0.77) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL8019337 | 0.80 | CASP3 (1.00) | CASP1CASP3CASP4CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001570-B2 | 6-amino-quinolinone compounds and derivatives as BCL6 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3555063-B1 | 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2020-09-16 | — | — | EP | disclosed |
| US-20200071297-A1 | NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2020-03-05 | — | — | US | disclosed |
| CN-104829608-B | A kind of cumarin thiazole indolone type compound and its preparation method and purposes | 吉首大学 | 2017-06-30 | — | — | CN | disclosed |
| CN-104829608-A | Coumarin-thiazole-indolone compounds, and preparation method and application thereof | UNIV JISHOU | 2015-08-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071297-A1 | NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BCL6, BCL6B, BCOR | CASP1 495/4885CASP3 251/4885CASP4 798/4885 |
| US-11001570-B2 | 6-amino-quinolinone compounds and derivatives as BCL6 inhibitors | BCL6, BCL6B, BCOR | CASP1 649/4885CASP3 278/4885CASP4 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.