SCHEMBL21775183

SCHEMBL21775183

CC1(C)CC(C)(c2ccc(N)cc2)c2cccc(N)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.39
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
LMNA P02545 3/20 0.37
KDM4E B2RXH2 2/20 0.37
OPRK1 P41145 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
FSHR P23945 1/20 0.35
ATM Q13315 1/20 0.33
POLB P06746 1/20 0.32
KDM1A O60341 1/20 0.32
ALDH1A1 P00352 4/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PLIN1 O60240 1/20 0.31
PLIN5 Q00G26 1/20 0.31
ABHD5 Q8WTS1 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ADRB2 P07550 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419154 0.87 CYP19A1 (0.39) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL807632 0.81 MEN1 (0.44) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL2686247 0.76 CYP19A1 (0.41) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL27862690 0.74 FSHR (0.44) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL29409547 0.72 FSHR (0.42) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL29374824 0.72 FSHR (0.42) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL137367 0.72 FSHR (0.42) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL140434 0.72 FSHR (0.42) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL27926236 0.71 FSHR (0.41) CYP19A1MEN1KMT2AMAPTLMNA
SCHEMBL27908100 0.71 FSHR (0.41) CYP19A1MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200075862-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2020-03-05 US claimed
CN-110740986-A Indane derivatives and their use in organic electronic devices 多蒂肯独家合成控股公司 2020-01-31 CN claimed
US-20240066778-A1 FLAME-RETARDANT CROSSLINKED ALIPHATIC POLYKETONES CARL FREUDENBERG KG (DE) 2024-02-29 US disclosed
US-20240066778-A1 FLAME-RETARDANT CROSSLINKED ALIPHATIC POLYKETONES CARL FREUDENBERG KG (DE) 2024-02-29 US disclosed
EP-3621946-B1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-09-06 EP disclosed
US-11495746-B2 Indane derivatives and their use in organic electronics DOTTIKON ES HOLDING AG (CH) 2022-11-08 US disclosed
US-11479629-B2 Crosslinking of polyaryletherketones FREUDENBERG SE (DE) 2022-10-25 US disclosed
US-20210309784-A1 CROSSLINKING OF POLYARYLETHERKETONES CARL FREUDENBERG KG (DE) 2021-10-07 US disclosed
WO-2021156403-A1 CROSS-LINKED ALIPHATIC POLYKETONES FREUDENBERG SE (DE) 2021-08-12 WO disclosed
US-20200075862-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2020-03-05 US disclosed
CN-110740986-A Indane derivatives and their use in organic electronic devices 多蒂肯独家合成控股公司 2020-01-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11495746-B2 Indane derivatives and their use in organic electronics KCNJ2, KCNA2, CYP2J2 CYP19A1 168/4885MEN1 2274/4885KMT2A 1499/4885
US-20200075862-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS KCNJ2, KCNA2, CYP2J2 CYP19A1 168/4885MEN1 2274/4885KMT2A 1499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.