Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161328 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAGAAKDM4ETDP1 | |
| SCHEMBL20139908 | 0.74 | CTDSP1 (0.44) | CTDSP1SMN1; SMN2LMNAGAAKDM4E | |
| SCHEMBL1128211 | 0.68 | KMT2A (0.52) | SMN1; SMN2LMNAGAAKDM4EKMT2A | |
| SCHEMBL20161464 | 0.67 | TAAR1 (0.38) | TDP1ALDH1A1NPC1TSHRL3MBTL1 | |
| SCHEMBL8638253 | 0.67 | ALDH1A1 (0.50) | SMN1; SMN2LMNAKDM4ETDP1KMT2A | |
| SCHEMBL27574624 | 0.66 | TACR1 (0.50) | LMNAKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6379502 | 0.66 | TACR1 (0.50) | LMNAKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL27461720 | 0.66 | TACR1 (0.50) | LMNAKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL28019866 | 0.66 | ALDH1A1 (0.49) | SMN1; SMN2LMNAGAAKDM4EKMT2A | |
| SCHEMBL28020287 | 0.66 | ALDH1A1 (0.49) | SMN1; SMN2LMNAGAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435080-B2 | sGC stimulators | TISENTO THERAPEUTICS INC. (US) | 2025-10-07 | — | — | US | disclosed |
| US-20220017515-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-20 | — | — | US | disclosed |
| US-20220017515-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-20 | — | — | US | disclosed |
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071318-A1 | SGC STIMULATORS | GUCY1A2, GMPS, PDE2A | CTDSP1 2844/4885SMN1; SMN2 1010/4885LMNA 3196/4885 |
| US-20220017515-A1 | sGC STIMULATORS | GUCY1A2, PRKG1, PDE2A | CTDSP1 2701/4885SMN1; SMN2 1049/4885LMNA 3153/4885 |
| US-12435080-B2 | sGC stimulators | GUCY1A2, PRKG1, PDE2A | CTDSP1 2701/4885SMN1; SMN2 1049/4885LMNA 3153/4885 |
| US-11180493-B2 | SGC stimulators | GUCY1A2, GMPS, PDE2A | CTDSP1 2844/4885SMN1; SMN2 1010/4885LMNA 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.