Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 12/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.55 |
| ▸ | CDK2 | P24941 | 9/20 | 0.55 |
| ▸ | CCR6 | P51684 | 7/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK14 | O94921 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.46 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK18 | Q07002 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177547 | 1.00 | CCNK (0.55) | CCNKCDK12CCNA2CDK2CCR6 | |
| SCHEMBL15204516 | 0.83 | HCAR3 (0.48) | CCNKCDK12CCNA2CDK2CCR6 | |
| SCHEMBL15204853 | 0.83 | HCAR3 (0.48) | CCNKCDK12CCNA2CDK2CCR6 | |
| SCHEMBL15204517 | 0.83 | HCAR3 (0.48) | CCNKCDK12CCNA2CDK2CCR6 | |
| SCHEMBL1937748 | 0.81 | IRAK4 (0.47) | — | |
| SCHEMBL1937750 | 0.81 | IRAK4 (0.47) | — | |
| SCHEMBL1937694 | 0.81 | HCAR3 (0.54) | CCR6 | |
| SCHEMBL1937691 | 0.81 | HCAR3 (0.54) | CCR6 | |
| SCHEMBL15717203 | 0.80 | CCNK (0.62) | CCNKCDK12CCNA2CDK2CCR6 | |
| SCHEMBL1936697 | 0.79 | GPR65 (0.38) | CCNKCDK12CCNA2CDK2CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166161-A1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166161-A1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS | ROCK1, ROCK2, RHOT2 | CCNK 3148/4885CDK12 1081/4885CCNA2 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.