SCHEMBL21776012

SCHEMBL21776012

CC(C)(N)C(=O)CCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.47
EGLN1 Q9GZT9 4/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
SLC15A2 Q16348 1/20 0.43
CYP1A2 P05177 2/20 0.41
THRB P10828 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GABRR1 P24046 2/20 0.40
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
FFAR3 O14843 1/20 0.39
KDM4E B2RXH2 4/20 0.39
PHF8 Q9UPP1 4/20 0.39
KDM2A Q9Y2K7 4/20 0.39
KDM5C P41229 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22625779 0.78 PHF8 (0.34) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL409946 0.78 EGLN1 (0.53) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL17378035 0.76 FAAH (0.44) LMNACYP1A2KMT2AMEN1TSHR
Succinic Acid SCHEMBL13724115 0.76 ALDH1A1 (0.54) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL12860094 0.76
Adipic Acid SCHEMBL15656240 0.74 LMNA (0.58) LMNATHRBKMT2AMEN1ALDH1A1
Succinic Acid SCHEMBL22346309 0.74 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL18630261 0.74 EGLN1 (0.47) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL1413213 0.74 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL147079 0.74 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020037434-A1 METHODS AND COMPOUNDS FOR TARGETING SORTILIN RECEPTORS AND INHIBITING VASCULOGENIC MIMICRY TRANSFERT PLUS, S.E.C. (CA) 2020-02-27 WO disclosed