Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.37 |
| ▸ | KDM5C | P41229 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976453 | 0.85 | SLC22A6 (0.52) | LMNAOR51E2SLC22A6TSHRNFKB1 | |
| SCHEMBL409946 | 0.78 | EGLN1 (0.53) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL21776012 | 0.74 | LMNA (0.47) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL10369361 | 0.74 | EGLN1 (0.47) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL18630072 | 0.73 | TSHR (0.35) | TSHR | |
| Succinic Acid SCHEMBL8052773 | 0.73 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL9837882 | 0.72 | LMNA (0.48) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL25407021 | 0.70 | CAMK2A (0.46) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL21087207 | 0.70 | FAAH (0.40) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Succinic Acid SCHEMBL3628497 | 0.69 | EGLN1 (0.82) | EGLN1LMNAALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | EGLN1 737/4885LMNA 1941/4885ALKBH5 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.