Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.48 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24038484 | 0.90 | HPGDS (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15333212 | 0.86 | KMT2A (0.53) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2902239 | 0.80 | CYP1A2 (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17648844 | 0.80 | CYP1A2 (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2148753 | 0.79 | GABRP (0.51) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4674699 | 0.78 | BAZ2B (0.53) | KMT2AMEN1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL14791060 | 0.77 | GABRA1 (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16453472 | 0.77 | CA12 (0.52) | KMT2AMEN1CYP3A4GABRA1GABRB2 | |
| SCHEMBL162674 | 0.77 | GABRP (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2518047 | 0.77 | BAZ2B (0.56) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195471-B | Polysubstituted pyridone derivative and application thereof in medicine | 苏州浦合医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110627796-B | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110520416-B | Polysubstituted pyridone derivative, preparation method and medical application thereof | 北京越之康泰生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113195471-A | Polysubstituted pyridone derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2020042618-A1 | MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |
| CN-110627796-A | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2019-12-31 | — | — | CN | disclosed |