Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776563 | 0.90 | KMT2A (0.50) | HPGDSGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL6242911 | 0.79 | NOTUM (0.53) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL18473811 | 0.77 | ALDH1A1 (0.45) | CYP1A2CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL15333212 | 0.77 | KMT2A (0.53) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL2148753 | 0.76 | GABRP (0.51) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL16453472 | 0.75 | CA12 (0.52) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL14791060 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL2518047 | 0.75 | BAZ2B (0.56) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL162674 | 0.75 | GABRP (0.50) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL5568378 | 0.75 | ALDH1A1 (0.51) | GABRA1GABRB2GABRB1GABRA3GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355107-A1 | MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF | BEIJING YUEZHIKANGTAI BIOMEDICINES CO LTD (CN) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355107-A1 | MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF | PDXK, ITK, JAK1 | HPGDS 1069/4885GABRA1 1967/4885GABRB2 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.