Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126431 | 0.84 | HTR1A (0.37) | DPP4SCN9AHTR2CSLC6A4HTR2A | |
| SCHEMBL22283641 | 0.79 | NAAA (0.40) | DPP4SCN9AHTR1ANAAA | |
| SCHEMBL22283644 | 0.79 | NAAA (0.40) | DPP4SCN9AHTR1ANAAA | |
| SCHEMBL28391073 | 0.78 | NAAA (0.40) | DPP4HTR1ANAAA | |
| SCHEMBL18615735 | 0.78 | NAAA (0.59) | SCN9AHTR1ANAAAKDM4EL3MBTL1 | |
| SCHEMBL30198976 | 0.76 | CXCR3 (0.49) | SCN9ANAAAKDM4EL3MBTL1DRD4 | |
| SCHEMBL18615766 | 0.76 | CARM1 (0.57) | HTR2CSLC6A4HTR2AHTR1AKDM4E | |
| SCHEMBL15536664 | 0.74 | SCN9A (0.54) | DPP4SCN9AHTR1ANAAAKDM4E | |
| SCHEMBL2101438 | 0.74 | NAAA (0.59) | HTR1ANAAAKDM4EL3MBTL1CARM1 | |
| SCHEMBL18579558 | 0.74 | DPP4 (0.40) | DPP4HTR2CSLC6A4HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |