Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 18/20 | 1.00 |
| ▸ | BMPR1A | P36894 | 18/20 | 1.00 |
| ▸ | ACVRL1 | P37023 | 18/20 | 1.00 |
| ▸ | ACVR1 | Q04771 | 18/20 | 1.00 |
| ▸ | TGFBR1 | P36897 | 17/20 | 0.84 |
| ▸ | MERTK | Q12866 | 2/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806978 | 1.00 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806979 | 1.00 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| Trifluoroacetic Acid SCHEMBL29373477 | 0.94 | BMPR1B (0.88) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL29370385 | 0.91 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19807056 | 0.91 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20067750 | 0.81 | BMPR1B (0.68) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20067749 | 0.81 | BMPR1B (0.68) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL18615504 | 0.81 | BMPR1B (0.68) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21779418 | 0.80 | BMPR1B (0.68) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806970 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014844-B | Aminopyridine derivatives and their use as selective ALK-2 inhibitors | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114014844-A | Aminopyridine derivatives and their use as selective ALK-2 inhibitors | 诺华股份有限公司 | 2022-02-08 | — | — | CN | disclosed |