Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | CREB1 | P16220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2160801 | 0.78 | HTT (0.42) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL21780155 | 0.78 | HTT (0.42) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL21780077 | 0.77 | ALDH1A1 (0.41) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL2298978 | 0.71 | HTT (0.41) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6197383 | 0.70 | HTT (0.42) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL21780072 | 0.66 | GRM2 (0.36) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL2161654 | 0.66 | GRM2 (0.36) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL20014862 | 0.66 | MEN1 (0.46) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL12239939 | 0.65 | HTT (0.39) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL24969604 | 0.65 | SLC22A2 (0.39) | LMNAGRM2GLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617194-A1 | PROCESSES AND INTERMEDIATES FOR CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS | VIIV Healthcare Company (US) | 2020-03-04 | — | — | EP | disclosed |