SCHEMBL21780103

SCHEMBL21780103

OCC(O)Oc1ccc(O)c(O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 4/20 0.41
ADRB1 P08588 2/20 0.41
PLA2G1B P04054 1/20 0.39
KDM6B O15054 1/20 0.38
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
APEX1 P27695 2/20 0.37
RECQL P46063 2/20 0.37
BLM P54132 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP3A4 P08684 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
ADRA2A P08913 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
ADRB3 P13945 1/20 0.37
DRD2 P14416 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917076 0.81 ESR2 (0.44) MAPTHPGDRECQLBLMKDM4E
SCHEMBL183507 0.80 TSHR (0.33) KMT2AMAPK1TSHR
SCHEMBL183508 0.74 MAOB (0.48) BLMCYP3A4TSHRCA1CA2
SCHEMBL10547022 0.74 HPGD (0.62) MAPTHPGDRECQLKDM4ECYP3A4
SCHEMBL26638222 0.73 ADRB2 (0.62) ADRB2ADRB1KDM4ELMNAADRB3
SCHEMBL4192132 0.72 ADRB2 (0.47) ADRB2ADRB1MAPTHPGDRECQL
SCHEMBL1052924 0.72 ALDH1A1 (0.52) ADRB2ADRB1RECQLKDM4EKMT2A
SCHEMBL10271635 0.72 PPARD (0.53) MAPTHPGDCYP3A4LMNAADORA3
SCHEMBL4188713 0.72 ADRB2 (0.44) ADRB2ADRB1MAPTHPGDRECQL
SCHEMBL109613 0.71 TDP1 (0.42) MAPTTDP1CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3271959-B1 PREPARATION OF TITANIUM CATECHOLATE COMPLEXES IN AQUEOUS SOLUTION USING TITANIUM TETRACHLORIDE OR TITANIUM OXYCHOLORIDE LOCKHEED MARTIN ENERGY LLC (US) 2020-03-04 EP disclosed