SCHEMBL8917076

SCHEMBL8917076

OCC(O)Oc1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ESR1 P03372 1/20 0.44
LTA4H P09960 4/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
HIF1A Q16665 3/20 0.38
PTGS1 P23219 2/20 0.38
SLC6A2 P23975 2/20 0.38
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
NFKB1 P19838 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183507 0.91 TSHR (0.33) KMT2ATSHR
SCHEMBL709832 0.86 ESR1 (0.53) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL21780103 0.81 ADRB2 (0.41) MEN1KMT2ALMNAPTGS2KDM4E
SCHEMBL109613 0.80 TDP1 (0.42) MEN1KMT2AALDH1A1CYP3A4MAPT
SCHEMBL11371209 0.80 LTA4H (0.47) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL28219139 0.80 TAAR1 (0.48) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL10748557 0.79 MEN1 (0.46) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL19309368 0.79 LMNA (0.43) LTA4HLMNAALDH1A1ALOX15CA5A
SCHEMBL242390 0.79 LMNA (0.43) LTA4HLMNAALDH1A1ALOX15CA5A
Water SCHEMBL9794578 0.78 TDP1 (0.41) MEN1KMT2AALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5683474-A HAIR DYES AND OXIDATION DYE PRECURSOR WITH OXIDIZERS L'OREAL (FR) 1997-11-04 US claimed
EP-0424261-B1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent OREAL (FR) 1996-01-03 EP claimed
EP-0269914-B1 COMPOSITION AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR ON THE BASIS OF 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES, AND 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES Wella Aktiengesellschaft (DE) 1991-06-12 EP claimed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP claimed
WO-1988004166-A1 HAIR DYEING OXIDISING AGENT AND PROCESS WITH 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES AND NEW 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES WELLA AKTIENGESELLSCHAFT (DE) 1988-06-16 WO claimed
CN-107001567-A It is used as the polyester prepolyer of the impact modifier in epoxy preparation SIKA技术股份公司 2017-08-01 CN disclosed
CN-103429439-A Non- pneumatic tire with annular spoke reinforcement CHEMTURA CORP 2013-12-04 CN disclosed
CN-101883689-B Non-pneumatic tire CHEMTURA CORP 2013-05-08 CN disclosed
EP-0424261-B1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent OREAL (FR) 1996-01-03 EP disclosed
EP-0459901-B1 Process for dyeing of keratinic fibres using 2,6-dimethyl-1,4-diaminobenzene and/or 2,6-diethyl-1,4-diaminobenzene in acid medium and compositions using this process OREAL (FR) 1995-12-13 EP disclosed
EP-0594811-A1 OXIDATION HAIR DYE BASED ON A CREAMY CARRIER AND PROCESS FOR DYEING HAIR. WELLA AG (DE) 1994-05-04 EP disclosed
WO-1993023006-A1 OXIDATION HAIR DYE BASED ON A CREAMY CARRIER AND PROCESS FOR DYEING HAIR WELLA AKTIENGESELLSCHAFT (DE) 1993-11-25 WO disclosed
EP-0459901-A1 Process for dyeing of keratinic fibres using 2,6-dimethyl-1,4-diaminobenzene and/or 2,6-diethyl-1,4-diaminobenzene in acid medium and compositions using this process L'OREAL (FR) 1991-12-04 EP disclosed
EP-0269914-B1 COMPOSITION AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR ON THE BASIS OF 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES, AND 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES Wella Aktiengesellschaft (DE) 1991-06-12 EP disclosed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP disclosed
US-4923479-A HAIR DYES WELLA AKTIENGESELLSCHAFT (DE) 1990-05-08 US disclosed
WO-1988004166-A1 HAIR DYEING OXIDISING AGENT AND PROCESS WITH 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES AND NEW 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES WELLA AKTIENGESELLSCHAFT (DE) 1988-06-16 WO disclosed