Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780429 | 0.76 | KCNK3 (0.46) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL21780486 | 0.69 | PTGDR2 (0.47) | KDM4EALDH1A1SLC6A7TSHRPTGDR2 | |
| SCHEMBL21780432 | 0.60 | TLR9 (0.43) | KDM4EALDH1A1TSHRKMT2AKCNK3 | |
| SCHEMBL17886713 | 0.59 | ALDH1A1 (0.72) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL21780503 | 0.59 | KCNK3 (0.43) | ALDH1A1TSHRKCNK3KCNK9PIK3CA | |
| SCHEMBL15853631 | 0.57 | RORC (0.64) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL15853648 | 0.56 | RORC (0.65) | KDM4EALDH1A1KMT2AKCNK3KCNK9 | |
| SCHEMBL15853630 | 0.56 | RORC (0.62) | LSSSIGMAR1 | |
| SCHEMBL21780426 | 0.55 | KMT2A (0.53) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL13974784 | 0.55 | RORC (0.65) | KDM4EALDH1A1LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |