Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780486 | 0.93 | PTGDR2 (0.47) | KCNK3KCNK9ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL21780432 | 0.85 | TLR9 (0.43) | KCNK3KCNK9ALDH1A1KDM4EKMT2A | |
| SCHEMBL21780503 | 0.83 | KCNK3 (0.43) | KCNK3KCNK9ALDH1A1HTTLMNA | |
| SCHEMBL21780426 | 0.81 | KMT2A (0.53) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL21780440 | 0.78 | LMNA (0.48) | KCNK3KCNK9KDM4EMEN1KMT2A | |
| SCHEMBL21780479 | 0.77 | LMNA (0.47) | KCNK3KCNK9ALDH1A1MEN1KMT2A | |
| SCHEMBL21780441 | 0.76 | LMNA (0.47) | KCNK3KCNK9MEN1KMT2ALMNA | |
| SCHEMBL21780491 | 0.76 | KDM4E (0.37) | KCNK3KCNK9ALDH1A1KDM4EMEN1 | |
| SCHEMBL21780420 | 0.74 | KMT2A (0.55) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL21780474 | 0.73 | GPR119 (0.51) | MEN1KMT2ALMNACFTRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |