Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780440 | 0.92 | LMNA (0.48) | TLR9TLR8TLR7TDP1LMNA | |
| SCHEMBL21780503 | 0.89 | KCNK3 (0.43) | ALDH1A1LMNATSHRKCNK3KCNK9 | |
| SCHEMBL21780426 | 0.88 | KMT2A (0.53) | ALDH1A1LMNATSHRGAAPOLB | |
| SCHEMBL21780429 | 0.85 | KCNK3 (0.46) | ALDH1A1LMNAKCNK3KCNK9POLB | |
| SCHEMBL21780479 | 0.83 | LMNA (0.47) | ALDH1A1LMNATSHRKCNK3KCNK9 | |
| SCHEMBL21780441 | 0.82 | LMNA (0.47) | LMNATSHRKCNK3KCNK9GAA | |
| SCHEMBL21780420 | 0.79 | KMT2A (0.55) | ALDH1A1LMNATSHRGAAPOLB | |
| SCHEMBL21780474 | 0.78 | GPR119 (0.51) | LMNATSHRPOLBKMT2A | |
| SCHEMBL21780486 | 0.78 | PTGDR2 (0.47) | ALDH1A1LMNATSHRKCNK3KCNK9 | |
| SCHEMBL21780417 | 0.76 | KCNH2 (0.49) | LMNATSHRGAAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |