Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21649652 | 0.88 | SIRT1 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4SIRT1 | |
| SCHEMBL22593891 | 0.85 | TRPV1 (0.45) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL21782007 | 0.84 | C3AR1 (0.37) | SIRT1SIRT2 | |
| SCHEMBL21782108 | 0.82 | SPHK1 (0.37) | — | |
| SCHEMBL23838548 | 0.81 | SIRT1 (0.37) | SIRT1GRIA1SIRT2 | |
| SCHEMBL22593908 | 0.81 | TRPV1 (0.46) | SIRT1GRIA1SIRT2 | |
| SCHEMBL22561449 | 0.81 | C3AR1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4SIRT1 | |
| SCHEMBL22214485 | 0.80 | SIRT2 (0.46) | SIRT1GRIA1SIRT2 | |
| SCHEMBL22593910 | 0.79 | TRPV1 (0.46) | — | |
| SCHEMBL25765429 | 0.77 | NPY5R (0.40) | SIRT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |