Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.38 |
| ▸ | FURIN | P09958 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782007 | 0.86 | C3AR1 (0.37) | C3AR1SIRT2SIRT1NPY1RADAM10 | |
| SCHEMBL21781914 | 0.81 | SPHK1 (0.42) | C3AR1SIRT1NPY1RADAM10MMP2 | |
| SCHEMBL21782008 | 0.81 | CHRNB2 (0.44) | SIRT2SIRT1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21649652 | 0.77 | SIRT1 (0.42) | SIRT2SIRT1FURINCHRNB2CHRNB4 | |
| SCHEMBL26273239 | 0.76 | SIRT2 (0.44) | SIRT2SIRT1SIRT3 | |
| SCHEMBL25774207 | 0.76 | SIRT2 (0.46) | SIRT2SIRT1SIRT3 | |
| SCHEMBL22214485 | 0.75 | SIRT2 (0.46) | SIRT2SIRT1SIRT3 | |
| SCHEMBL22810892 | 0.75 | SIRT2 (0.41) | C3AR1SIRT2SIRT1SIRT3ADAM10 | |
| SCHEMBL22593891 | 0.75 | TRPV1 (0.45) | NPY1R | |
| SCHEMBL18811657 | 0.74 | CA1 (0.48) | C3AR1SIRT2SIRT1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725798-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-10-21 | — | — | EP | disclosed |