Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901378 | 0.86 | ADAM10 (0.38) | SIRT1SIRT2SIRT3 | |
| SCHEMBL21782008 | 0.81 | CHRNB2 (0.44) | SIRT1SIRT2GRIA1 | |
| SCHEMBL21649652 | 0.78 | SIRT1 (0.42) | SIRT1SIRT2GRIA1 | |
| SCHEMBL22593891 | 0.77 | TRPV1 (0.45) | GRIA1 | |
| SCHEMBL24115692 | 0.77 | SIRT2 (0.37) | SIRT1SIRT2SIRT3 | |
| SCHEMBL20880212 | 0.77 | SIRT2 (0.44) | SIRT1SIRT2SIRT3GRIA1 | |
| SCHEMBL22214485 | 0.76 | SIRT2 (0.46) | SIRT1SIRT2SIRT3GRIA1 | |
| SCHEMBL23739148 | 0.76 | SIRT2 (0.43) | SIRT1SIRT2SIRT3GRIA1 | |
| SCHEMBL21782007 | 0.74 | C3AR1 (0.37) | SIRT1SIRT2 | |
| SCHEMBL20880254 | 0.74 | SIRT2 (0.39) | SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057610-B1 | DRUG-CONJUGATES WITH A TARGETING MOLECULE AND TWO DIFFERENT DRUGS | SORRENTO THERAPEUTICS INC (US) | 2021-09-22 | — | — | EP | disclosed |