Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 9/20 | 0.33 |
| ▸ | NPY4R | P50391 | 6/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561449 | 0.86 | C3AR1 (0.43) | C3AR1ADAM10MMP2MMP9MMP12 | |
| SCHEMBL21782008 | 0.84 | CHRNB2 (0.44) | SIRT1SIRT2 | |
| SCHEMBL21781914 | 0.82 | SPHK1 (0.42) | C3AR1ADAM10MMP2MMP9MMP12 | |
| SCHEMBL21782000 | 0.80 | ITGB1 (0.34) | C3AR1 | |
| SCHEMBL21781895 | 0.80 | SIRT2 (0.33) | SIRT5QRFPRSIRT1SIRT2 | |
| SCHEMBL21649652 | 0.80 | SIRT1 (0.42) | SIRT1SIRT2 | |
| SCHEMBL21781923 | 0.80 | QRFPR (0.42) | C3AR1QRFPR | |
| SCHEMBL22593910 | 0.78 | TRPV1 (0.46) | QRFPRNPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL22593891 | 0.77 | TRPV1 (0.45) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL16274143 | 0.77 | ROCK2 (0.44) | NPY1RNPY4RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |