Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 5/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782071 | 0.82 | ITGB1 (0.34) | MMP7ITGB1ITGA5AKT1KDM1A | |
| SCHEMBL21781797 | 0.82 | AKT1 (0.39) | MMP7ITGB1ITGA5AKT1HRH1 | |
| SCHEMBL21782018 | 0.80 | AKT1 (0.37) | MMP7ITGB1ITGA5AKT1HRH1 | |
| SCHEMBL21781742 | 0.80 | MMP7 (0.32) | MMP7ITGB1ITGA5ITGA4 | |
| SCHEMBL21781814 | 0.75 | AKT1 (0.31) | ITGB1ITGA5AKT1 | |
| SCHEMBL21781807 | 0.73 | CYP3A4 (0.31) | ITGB1AKT1ITGA4 | |
| SCHEMBL21782047 | 0.73 | — | — | |
| SCHEMBL21781748 | 0.73 | KMT2A (0.31) | MMP7ITGB1ITGA5KMT2AMEN1 | |
| SCHEMBL21782101 | 0.71 | AKT1 (0.39) | ITGB1ITGA5AKT1KMT2AMEN1 | |
| SCHEMBL22068095 | 0.69 | MAP1LC3B (0.36) | ITGB1HRH1KMT2AMEN1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |