Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.41 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.41 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | RRM2 | P31350 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230165 | 0.82 | SUMO3 (0.43) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL20457670 | 0.77 | POLB (0.42) | RAB9AMAPTKMT2AGAAKDM4E | |
| SCHEMBL8434004 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL2814675 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL7886636 | 0.73 | CASP6 (0.35) | RAB9AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL20457772 | 0.73 | GRM5 (0.37) | SMN1; SMN2RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL9432628 | 0.72 | RAB9A (0.50) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9656952 | 0.72 | KDM4E (0.51) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL3805672 | 0.72 | KDM4E (0.45) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL2946120 | 0.71 | DHODH (0.54) | SMN1; SMN2RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617192-A1 | VIRAL REPLICATION INHIBITORS | Katholieke Universiteit Leuven K.U. Leuven R&D (BE) | 2020-03-04 | — | — | EP | disclosed |