Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.46 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2814675 | 0.75 | ALDH1A1 (0.49) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL8434004 | 0.75 | SMN1; SMN2 (0.49) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL7702093 | 0.74 | ADRB2 (0.47) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL2946120 | 0.73 | DHODH (0.54) | KDM4EHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8885746 | 0.73 | KDR (0.47) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL21782258 | 0.72 | SMN1; SMN2 (0.43) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL17612628 | 0.72 | KDM4E (0.44) | KDM4EHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11212892 | 0.71 | ADRB2 (0.39) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL3805672 | 0.71 | KDM4E (0.45) | KDM4EHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL2230165 | 0.71 | SUMO3 (0.43) | KDM4EHTTSMN1; SMN2LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171858-A | Preparation of certain 5,6-dihydro-8-phenyl-imidazo[1,5-a]pyridines | SCHERING A.G. (DE) | 1992-12-15 | — | — | US | disclosed |
| US-5026712-A | Novel imidazo[1,5-a]pyridines, useful as cardiovascular and CNS agents | SCHERING AG (DE) | 1991-06-25 | — | — | US | disclosed |