Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782635 | 0.90 | PAOX (0.42) | PAOXALDH1A1DPP7KDM4ESMN1; SMN2 | |
| SCHEMBL21782634 | 0.86 | DPP7 (0.33) | PAOXALDH1A1DPP7LMNASLC22A2 | |
| SCHEMBL20620313 | 0.86 | NPY4R (0.32) | PAOXALDH1A1KDM4ESMN1; SMN2NPY4R | |
| SCHEMBL16263596 | 0.85 | SIRT1 (0.33) | PAOXALDH1A1DPP7LMNASLC22A2 | |
| SCHEMBL21782715 | 0.85 | DPP7 (0.39) | ALDH1A1DPP7KDM4ESMN1; SMN2LMNA | |
| SCHEMBL21782740 | 0.82 | NPY4R (0.32) | DPP7SMN1; SMN2CNR1RRM1NPY4R | |
| SCHEMBL21782662 | 0.78 | DPP7 (0.41) | PAOXDPP7SMN1; SMN2CNR1RRM1 | |
| SCHEMBL20169777 | 0.77 | DPP7 (0.51) | DPP7CNR1RRM1 | |
| SCHEMBL21782696 | 0.77 | GNAI3 (0.41) | PAOXDPP7SMN1; SMN2CNR1RRM1 | |
| SCHEMBL20072809 | 0.76 | DPP7 (0.53) | DPP7CNR1RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |