Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.32 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | NPY2R | P49146 | 3/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782715 | 0.90 | DPP7 (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL21782579 | 0.86 | DPP7 (0.32) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL16263611 | 0.85 | NPY4R (0.34) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL16263598 | 0.85 | CACNA1B (0.36) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21782662 | 0.82 | DPP7 (0.41) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL21782577 | 0.82 | PAOX (0.33) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL21782696 | 0.81 | GNAI3 (0.41) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL16263607 | 0.78 | SIRT6 (0.38) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL20169777 | 0.78 | DPP7 (0.51) | DPP7CNR1RRM1 | |
| SCHEMBL27354286 | 0.77 | ALOX15 (0.37) | NPY4RNPY1RNPY2RNPY5RDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |