Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782577 | 0.86 | PAOX (0.33) | DPP7PAOXALDH1A1RRM1TSHR | |
| SCHEMBL16263596 | 0.84 | SIRT1 (0.33) | DPP7PAOXALDH1A1TSHRLMNA | |
| SCHEMBL21782580 | 0.84 | DPP7 (0.36) | DPP7ALDH1A1RRM1LMNAGNAI3 | |
| SCHEMBL20620313 | 0.82 | NPY4R (0.32) | PAOXALDH1A1 | |
| SCHEMBL21782579 | 0.81 | DPP7 (0.32) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL21782697 | 0.79 | DNM1 (0.37) | DPP7PAOXALDH1A1RRM1GNAI3 | |
| SCHEMBL21782630 | 0.77 | GNAI3 (0.39) | DPP7PAOXALDH1A1RRM1GNAI3 | |
| SCHEMBL21782581 | 0.77 | DPP7 (0.38) | DPP7PAOXALDH1A1RRM1GNAI3 | |
| SCHEMBL21782635 | 0.77 | PAOX (0.42) | DPP7PAOXALDH1A1LMNA | |
| SCHEMBL21782715 | 0.73 | DPP7 (0.39) | DPP7ALDH1A1RRM1LMNAGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |