Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19429648 | 0.83 | PHGDH (0.48) | NPC1PHGDHMGLLALDH1A1HPGD | |
| SCHEMBL15086040 | 0.79 | NPC1 (0.43) | NPC1PHGDHMGLLALDH1A1HPGD | |
| SCHEMBL3306436 | 0.78 | L3MBTL1 (0.43) | NPC1PHGDHMGLLALDH1A1HPGD | |
| SCHEMBL26571265 | 0.77 | THRA (0.35) | — | |
| SCHEMBL24905681 | 0.76 | PHGDH (0.42) | NPC1PHGDHMGLLALDH1A1HPGD | |
| SCHEMBL21782877 | 0.76 | DPP4 (0.41) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL14224955 | 0.76 | MEN1 (0.47) | NPC1PHGDHMGLLALDH1A1HPGD | |
| SCHEMBL22540331 | 0.76 | MEN1 (0.31) | NPC1MAPTKMT2AMEN1POLB | |
| SCHEMBL3308433 | 0.76 | L3MBTL1 (0.45) | NPC1PHGDHMGLLALDH1A1HPGD | |
| SCHEMBL14433862 | 0.75 | NPC1 (0.47) | NPC1PHGDHMGLLALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |