Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783525 | 0.71 | TAS2R14 (0.39) | APLNR | |
| SCHEMBL21783403 | 0.65 | QPCT (0.32) | APLNRQPCTSCN1ASCN2ASCN3A | |
| SCHEMBL21783460 | 0.62 | ALDH1A1 (0.34) | APLNR | |
| Hydrogen Sulfide SCHEMBL21793924 | 0.62 | MEN1 (0.33) | QPCT | |
| SCHEMBL30708503 | 0.61 | LMNA (0.42) | APLNRQPCTSCN1ASCN2ASCN3A | |
| SCHEMBL21773265 | 0.61 | CNR2 (0.41) | APLNR | |
| SCHEMBL26694482 | 0.59 | MEN1 (0.42) | APLNRQPCTSCN1ASCN2ASCN3A | |
| SCHEMBL30484799 | 0.56 | LMNA (0.42) | APLNRQPCTSCN1ASCN2ASCN3A | |
| SCHEMBL25886346 | 0.56 | LMNA (0.42) | APLNRQPCTSCN1ASCN2ASCN3A | |
| SCHEMBL12093307 | 0.56 | NCF1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |