SCHEMBL21784356

SCHEMBL21784356

CC(C)(C)OC(=O)N(C1CC1)C1CCN(C(=O)C(F)(F)F)CC1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.46
HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23867772 0.89 GPR119 (0.41) GPR119HSD11B1
SCHEMBL21626611 0.80 GPR119 (0.40) GPR119HSD11B1
SCHEMBL21784350 0.79 KDM1A (0.50) GPR119HSD11B1
SCHEMBL19025342 0.79 KDM1A (0.50) GPR119HSD11B1
SCHEMBL21784353 0.79 KDM1A (0.50) GPR119HSD11B1
SCHEMBL21784423 0.79 KDM1A (0.50) GPR119HSD11B1
SCHEMBL10313873 0.78 PDK2 (0.36) GPR119HSD11B1
SCHEMBL15507268 0.77 GPR119 (0.55) GPR119
SCHEMBL24165429 0.76 HSD11B1 (0.39) GPR119HSD11B1
SCHEMBL6128193 0.75 CTSK (0.49) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020047198-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME INCYTE CORPORATION (US) 2020-03-05 WO disclosed