Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19067400 | 0.83 | KDM4E (0.44) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL20153618 | 0.83 | MEN1 (0.39) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL20272361 | 0.81 | CHRM1 (0.37) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL14922889 | 0.79 | CHRM1 (0.35) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL22421787 | 0.79 | KDM4E (0.41) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL16281504 | 0.76 | ACHE (0.40) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL27855844 | 0.73 | MAOA (0.56) | MEN1KMT2AKDM4EMAOAMIF | |
| SCHEMBL19293332 | 0.72 | KDM4E (0.39) | MEN1KMT2AKDM4EACHEMAOA | |
| SCHEMBL20687370 | 0.72 | MAPT (0.40) | MEN1KMT2AKDM4EMAOAMIF | |
| SCHEMBL25703544 | 0.71 | KDM4E (0.66) | MEN1KMT2AKDM4EACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787779-B2 | Sulfone pyridine alkyl amide-substituted heteroaryl compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-11597721-B2 | Heterocyclic compounds comprising pyridine useful as modulators of IL-12, IL-23 and/or IFNα responses | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-03-07 | — | — | US | disclosed |
| US-11021475-B2 | Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200321525-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | MATERIAL SCIENCE CO., LTD. (KR) | 2020-10-08 | — | — | US | disclosed |
| US-20200071315-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL-MYERS SQUIBB COMPANY | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021475-B2 | Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses | IFNG, IFNAR1, TYK2 | MEN1 3673/4885KMT2A 1342/4885KDM4E 2185/4885 |
| US-20200321525-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | OR10J3, OR51E2, ORC3 | MEN1 2380/4885KMT2A 1074/4885KDM4E 1082/4885 |
| US-11787779-B2 | Sulfone pyridine alkyl amide-substituted heteroaryl compounds | TYK2, JAK3, JAK2 | MEN1 3767/4885KMT2A 1460/4885KDM4E 1208/4885 |
| US-11597721-B2 | Heterocyclic compounds comprising pyridine useful as modulators of IL-12, IL-23 and/or IFNα responses | TYK2, IL23R, JAK3 | MEN1 3337/4885KMT2A 2007/4885KDM4E 1977/4885 |
| US-20200071315-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | IFNG, IFNAR1, TYK2 | MEN1 3673/4885KMT2A 1342/4885KDM4E 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.