Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798825 | 0.84 | CYP3A4 (0.53) | LMNAGAATSHRKDM4EALDH1A1 | |
| SCHEMBL21780647 | 0.80 | LMNA (0.43) | LMNAGAATSHRKDM4ERBP4 | |
| SCHEMBL21785002 | 0.79 | LMNA (0.34) | LMNAGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL2549619 | 0.76 | LMNA (0.60) | LMNAGAATSHRKDM4EALDH1A1 | |
| SCHEMBL303839 | 0.75 | GAA (0.61) | LMNAGAATSHRALDH1A1KMT2A | |
| SCHEMBL1829881 | 0.75 | GAA (0.61) | LMNAGAATSHRALDH1A1KMT2A | |
| SCHEMBL2547997 | 0.75 | GAA (0.61) | LMNAGAATSHRKDM4EALDH1A1 | |
| SCHEMBL2227113 | 0.73 | LMNA (0.96) | LMNAGAATSHRKDM4EALDH1A1 | |
| SCHEMBL628330 | 0.73 | LMNA (0.96) | LMNAGAATSHRKDM4EALDH1A1 | |
| SCHEMBL27974791 | 0.73 | GAA (0.58) | LMNAGAATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047239-A1 | INHIBITING αV β6 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |