Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21784698 | 0.80 | LMNA (0.55) | LMNAGAATSHRRBP4KDM4E | |
| SCHEMBL7401885 | 0.70 | GAA (0.70) | LMNAGAATSHRKDM4ECYP3A4 | |
| SCHEMBL3466786 | 0.70 | LMNA (0.66) | LMNAGAACYP3A4KCNA5KCNH2 | |
| SCHEMBL21780658 | 0.69 | LMNA (0.39) | LMNAGAAKDM4ECYP3A4 | |
| SCHEMBL30053721 | 0.68 | KDM4C (0.48) | RBP4KDM4E | |
| SCHEMBL20314858 | 0.68 | IDO1 (0.39) | CYP17A1IDO1 | |
| SCHEMBL2453996 | 0.66 | RBP4 (0.49) | RBP4CYP46A1KDM4ECYP2C9 | |
| SCHEMBL7798825 | 0.66 | CYP3A4 (0.53) | LMNAGAATSHRKDM4ECYP3A4 | |
| SCHEMBL25220711 | 0.65 | OPRL1 (0.34) | CYP17A1IDO1 | |
| SCHEMBL30488141 | 0.65 | OPRL1 (0.34) | CYP17A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617206-A1 | INTEGRIN INHIBITORS | Morphic Therapeutic, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |