Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP27B1 | O15528 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | CCR1 | P32246 | 5/20 | 0.32 |
| ▸ | CCR2 | P41597 | 5/20 | 0.32 |
| ▸ | CCR4 | P51679 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20363965 | 0.84 | CYP3A4 (0.35) | CYP27B1OGG1CYP19A1CYP3A4TSHR | |
| SCHEMBL21772447 | 0.81 | OGG1 (0.38) | CYP27B1OGG1CYP19A1CCR1CCR2 | |
| SCHEMBL20365770 | 0.80 | CYP3A4 (0.46) | OGG1CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11129469 | 0.77 | OGG1 (0.38) | CYP27B1OGG1CYP19A1CCR1CCR2 | |
| SCHEMBL1423792 | 0.77 | CYP27B1 (0.38) | CYP27B1OGG1CYP19A1CCR1CCR2 | |
| SCHEMBL9657759 | 0.77 | CYP3A4 (0.40) | OGG1CYP19A1CCR1CCR2CCR4 | |
| SCHEMBL10572265 | 0.74 | CYP27B1 (0.36) | CYP27B1OGG1CYP19A1CCR1CCR2 | |
| SCHEMBL6707593 | 0.73 | CYP19A1 (0.36) | CYP27B1OGG1CYP19A1CCR1CCR2 | |
| SCHEMBL10917973 | 0.72 | OGG1 (0.45) | CYP27B1OGG1CYP19A1CCR1CCR2 | |
| SCHEMBL10923524 | 0.72 | CYP27B1 (0.37) | CYP27B1OGG1CYP19A1CCR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200072711-A1 | FLUORESCENT ENDOPLASMIC RETICULUM TRACKERS FOR LIVE CELL IMAGING OF PATHOGENIC YEAST | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2020-03-05 | — | — | US | disclosed |