Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 3/20 | 0.33 |
| ▸ | CCND1 | P24385 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707592 | 0.82 | CYP3A4 (0.45) | CYP19A1OGG1KMT2ACYP3A4PTGS2 | |
| SCHEMBL21772447 | 0.79 | OGG1 (0.38) | CYP19A1CYP27B1CCR1CCR2OGG1 | |
| SCHEMBL11129469 | 0.75 | OGG1 (0.38) | CYP19A1SMN1; SMN2CYP27B1CCR1CCR2 | |
| SCHEMBL1423792 | 0.75 | CYP27B1 (0.38) | CYP19A1CYP27B1CCR1CCR2OGG1 | |
| SCHEMBL21784832 | 0.73 | CYP27B1 (0.35) | CYP19A1CYP27B1CCR1CCR2OGG1 | |
| SCHEMBL10923524 | 0.72 | CYP27B1 (0.37) | CYP19A1CYP27B1CCR1CCR2OGG1 | |
| SCHEMBL9657759 | 0.72 | CYP3A4 (0.40) | CYP19A1CCR1CCR2OGG1CYP3A4 | |
| SCHEMBL10572265 | 0.72 | CYP27B1 (0.36) | CYP19A1CYP27B1CCR1CCR2OGG1 | |
| SCHEMBL10917973 | 0.70 | OGG1 (0.45) | CYP19A1MAPTCYP27B1CCR1CCR2 | |
| SCHEMBL9662961 | 0.70 | CYP3A4 (0.44) | CYP19A1CYP27B1CCR1CCR2OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | CYP19A1 1538/4885MAPT 1200/4885SMN1; SMN2 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.