SCHEMBL21785663

SCHEMBL21785663

O=C(Oc1ccccc1)Oc1cccc(-c2ccccc2O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
BCL2L1 Q07817 1/20 0.50
ALOX15 P16050 1/20 0.45
ESR2 Q92731 1/20 0.44
PTPN5 P54829 1/20 0.43
NSD2 O96028 1/20 0.42
KDM1A O60341 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
EPHX1 P07099 1/20 0.40
MAPT P10636 1/20 0.40
PPARG P37231 1/20 0.40
KMT2A Q03164 1/20 0.40
NCOA2 Q15596 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylphenol SCHEMBL246847 0.90 HPGD (0.63) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL22003014 0.85 HPGD (0.55) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL27999721 0.84 CYP3A4 (0.57) HPGDHSD17B10ALDH1A1BCL2L1HDAC4
SCHEMBL21848015 0.83 EPHX1 (0.54) EPHX1MAPTFABP7FABP3FABP5
SCHEMBL29053641 0.81 EPHX1 (0.55) EPHX1FABP7FABP3FABP5
SCHEMBL1674296 0.81 HPGD (0.46) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL7035319 0.80 ACHE (0.52) HPGDHSD17B10ALDH1A1BCL2L1ESR2
2-Phenylphenol SCHEMBL246850 0.80 HPGD (0.63) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL10596262 0.78 KMT2A (0.58) HPGDHSD17B10ALDH1A1ALOX15NSD2
SCHEMBL17697663 0.77 BACE1 (0.47) EPHX1FABP7FABP3FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200071461-A1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2020-03-05 US disclosed