2-Phenylphenol

2-Phenylphenol

SCHEMBL246847

O=C(Oc1ccccc1)Oc1ccccc1.Oc1ccccc1-c1ccccc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.63
HSD17B10 Q99714 2/20 0.63
ALDH1A1 P00352 1/20 0.63
BCL2L1 Q07817 1/20 0.63
ALOX15 P16050 1/20 0.50
BACE1 P56817 2/20 0.43
NSD2 O96028 1/20 0.43
ALOX5 P09917 1/20 0.42
MAOA P21397 1/20 0.42
HNF4A P41235 1/20 0.42
HDAC6 Q9UBN7 2/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
ESR2 Q92731 1/20 0.41
EGFR P00533 1/20 0.41
BRD4 O60885 1/20 0.40
NR1I2 O75469 1/20 0.40
SMARCA2 P51531 1/20 0.40
SMARCA4 P51532 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22003014 0.95 HPGD (0.55) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL21785663 0.90 HPGD (0.50) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
2-Phenylphenol SCHEMBL246850 0.89 HPGD (0.63) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL1674296 0.86 HPGD (0.46) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
2-Phenylphenol SCHEMBL27504029 0.82 ALDH1A1 (0.85) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
Biphenyl SCHEMBL6843812 0.82 TDP1 (0.48) HPGDHSD17B10ALDH1A1ALOX15L3MBTL1
2-Phenylphenol SCHEMBL2415939 0.82 ALDH1A1 (0.85) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL246848 0.81 FABP3 (0.50) ALDH1A1ALOX15BACE1BCAT2L3MBTL1
SCHEMBL17697654 0.81 BACE1 (0.49) HPGDHSD17B10ALDH1A1ALOX15BACE1
2-Phenylphenol SCHEMBL11403217 0.80 ALDH1A1 (0.74) HPGDHSD17B10ALDH1A1BCL2L1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
US-20190143582-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING COVESTRO DEUTSCHLAND AG (DE) 2019-05-16 US disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
EP-3452530-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING Covestro Deutschland AG (DE) 2019-03-13 EP disclosed
US-20180179378-A1 Copolycarbonate Compositions with Cyclic and Linear Oligomers and Improved Optical Properties COVESTRO DEUTSCHLAND AG (DE) 2018-06-28 US disclosed
US-9969879-B2 Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties COVESTRO DEUTSCHLAND AG (DE) 2018-05-15 US disclosed
US-20170362431-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
US-20170355817-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED PROCESSING BEHAVIOUR CONTAINING PE-WAX COVESTRO DEUTSCHLAND AG (DE) 2017-12-14 US disclosed
US-7132497-B2 Aromatic dihydroxy compound useful for the preparation of (CO)polycarbonates BAYER MATERIALSCIENCE AKTIENGESELLSCHAFT (DE) 2006-11-07 US disclosed
US-6916899-B2 Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols BAYER AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20050054808-A1 Novel aromatic dihydroxy compound useful for the preparation of (CO)polycarbonates BAYER MATERIALSCIENCE AG (DE) 2005-03-10 US disclosed
US-6835797-B2 Reacting a dihydroxyaryl compound with a diaryl carbonate to obtain a melt; flash evaporation of the monohydroxyaryl compound; heating the melt under vacuum; and repeating the steps BAYER AKTIENGESELLSCHAFT (DE) 2004-12-28 US disclosed
US-20040158025-A1 Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols BAYER AKTIENGESELLSCHAFT (DE) 2004-08-12 US disclosed
US-20040127677-A1 Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols BAYER AKTIENGESELLSCHAFT (DE) 2004-07-01 US disclosed
US-6753405-B2 MORE THAN 35 MOLE % OF UNITS DERIVED FROM DIHYDROXYDIPHENYLENE AND THE REST FROM AN ALKYLIDENE OR CYCLOALKYLIDENE BISPHENOL; PREPARED BY MELT TRANSESTERIFICATION; USED TO PREPARE TRANSPARENT MOLDINGS BAYER AKTIENGESELLSCHAFT (DE) 2004-06-22 US disclosed
US-20030055201-A1 Process for optimising the production of polycarbonate by melt transesterification BAYER AKTIENGESELLSCHAFT (DE) 2003-03-20 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed