Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674298 | 0.90 | HPGD (0.46) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| 2-Phenylphenol SCHEMBL246847 | 0.86 | HPGD (0.63) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| Bicarbonate SCHEMBL246690 | 0.84 | ALDH1A1 (0.58) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| SCHEMBL1674297 | 0.84 | HNF4A (0.41) | HSD17B10ALDH1A1HNF4ABACE1HDAC4 | |
| SCHEMBL18150 | 0.82 | ALDH1A1 (0.65) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| SCHEMBL22003014 | 0.81 | HPGD (0.55) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| Formaldehyde SCHEMBL29141444 | 0.81 | ALDH1A1 (0.58) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| SCHEMBL21785663 | 0.81 | HPGD (0.50) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| SCHEMBL23329593 | 0.80 | ALDH1A1 (0.62) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 | |
| SCHEMBL28918851 | 0.80 | ALDH1A1 (0.62) | HPGDHSD17B10ALDH1A1BCL2L1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232644-A1 | PRODUCTS WITH IMPROVED NON-FLAMMABILITY | COVESTRO DEUTSCHLAND AG (DE) | 2015-08-20 | — | — | US | disclosed |
| WO-2012085112-A1 | POLYCARBONATE COMPOSITIONS WITH IMPROVED FLAME RESISTANCE | BAYER MATERIALSCIENCE AG (DE) | 2012-06-28 | — | — | WO | disclosed |
| EP-2468820-A1 | Polycarbonate compositions with improved flame resistance | Bayer MaterialScience AG (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-20110098386-A1 | PRODUCTS HAVING IMPROVED FLAME RESISTANCE | BAYER MATERIALSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |