Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754818 | 0.92 | CTSS (0.40) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL24113318 | 0.92 | CTSS (0.40) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL25134723 | 0.92 | CTSS (0.40) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL19586956 | 0.91 | IDO1 (0.50) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL19586958 | 0.91 | IDO1 (0.50) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL19586954 | 0.91 | IDO1 (0.50) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL24584247 | 0.89 | NFKB1 (0.41) | CTSSCTSKIDO1 | |
| SCHEMBL24754820 | 0.89 | NFKB1 (0.41) | CTSSCTSKIDO1 | |
| SCHEMBL24963813 | 0.89 | NFKB1 (0.41) | CTSSCTSKIDO1 | |
| SCHEMBL19606034 | 0.89 | NFKB1 (0.41) | CTSSCTSKIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021513-B2 | Peptidomimetics for the treatment of norovirus infection | EMORY UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200071354-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF NOROVIRUS INFECTION | EMORY UNIVERSITY (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021513-B2 | Peptidomimetics for the treatment of norovirus infection | VIP, HAVCR2, NGLY1 | CTSS 813/4885CTSK 1215/4885IDO1 2265/4885 |
| US-20200071354-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF NOROVIRUS INFECTION | VIP, HAVCR2, NGLY1 | CTSS 813/4885CTSK 1215/4885IDO1 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.