Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616087 | 0.90 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDGLP1R | |
| SCHEMBL23106273 | 0.90 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL21786796 | 0.88 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL21575544 | 0.88 | HPGD (0.43) | MEN1KMT2AHPGDCYP2D6CYP2C19 | |
| SCHEMBL23879753 | 0.88 | MEN1 (0.45) | MEN1KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL21029891 | 0.87 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDGLP1R | |
| SCHEMBL23334288 | 0.87 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDGLP1R | |
| SCHEMBL11912094 | 0.87 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDGLP1R | |
| SCHEMBL11912095 | 0.87 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDGLP1R | |
| SCHEMBL25834766 | 0.87 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697736-B2 | Silicon containing detectable compounds | Singular Genomics Systems, Inc. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | disclosed |
| US-20230011240-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-12 | — | — | US | disclosed |
| US-11535754-B2 | Silicon containing detectable compounds and uses thereof | Singular Genomics Systems, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
| US-20220119779-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| US-20210284975-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2021-09-16 | — | — | US | disclosed |
| US-11034942-B1 | Modified pyrococcus polymerases and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697736-B2 | Silicon containing detectable compounds | AS3MT, SCLY, NASP | MEN1 660/4885KMT2A 3136/4885ALDH1A1 1169/4885 |
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, RNGTT | MEN1 3489/4885KMT2A 1738/4885ALDH1A1 1026/4885 |
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, NUDT1 | MEN1 3223/4885KMT2A 1863/4885ALDH1A1 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.