Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23998926 | 0.81 | CRHR1 (0.37) | MAPK1TDP1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL17000219 | 0.81 | AGBL2 (0.40) | AGBL2ALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL26199719 | 0.79 | AGBL2 (0.54) | AGBL2KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL17002597 | 0.79 | CPB2 (0.33) | MEN1KMT2A | |
| SCHEMBL364169 | 0.78 | HSD17B10 (0.37) | TDP1L3MBTL1ALDH1A1NPSR1MEN1 | |
| SCHEMBL17000220 | 0.77 | TDP1 (0.54) | MAPK1TDP1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL19583872 | 0.76 | AGBL2 (0.38) | AGBL2OPRL1MAPK1BACE1TDP1 | |
| SCHEMBL17768622 | 0.75 | AGBL2 (0.37) | AGBL2OPRL1MAPK1BACE1TDP1 | |
| SCHEMBL23530950 | 0.75 | AGBL2 (0.37) | AGBL2OPRL1MAPK1BACE1TDP1 | |
| SCHEMBL23874363 | 0.75 | SLC22A12 (0.41) | AGBL2OPRL1MAPK1BACE1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2020046813-A1 | CD73 INHIBITORS | ARCUS BIOSCIENCES, INC. (US) | 2020-03-05 | — | — | WO | disclosed |