Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266187 | 0.83 | APAF1 (0.38) | APAF1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL21787597 | 0.82 | — | — | |
| SCHEMBL12228330 | 0.81 | APAF1 (0.39) | APAF1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL15905729 | 0.80 | APAF1 (0.41) | APAF1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL21787528 | 0.76 | APAF1 (0.36) | APAF1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL21787488 | 0.75 | FOLH1 (0.39) | FOLH1 | |
| SCHEMBL3236355 | 0.73 | GABRR1 (0.39) | APAF1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL11702665 | 0.73 | TDP1 (0.36) | — | |
| SCHEMBL11307127 | 0.72 | APAF1 (0.36) | APAF1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL22034668 | 0.72 | ADRB2 (0.39) | APAF1GABRR1CYP1A2FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246344-A1 | Biological buffers with wide buffering ranges | DALY THOMAS (US) | 2021-08-12 | — | — | US | disclosed |
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | APAF1 1850/4885GABRR1 625/4885CYP1A2 4877/4885 |
| US-20210246344-A1 | Biological buffers with wide buffering ranges | PEF1, SLC7A1, PLPBP | APAF1 1886/4885GABRR1 636/4885CYP1A2 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.