SCHEMBL3236355

SCHEMBL3236355

CC(CN[C@](C)(N)C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.39
APAF1 O14727 1/20 0.37
CYP1A2 P05177 1/20 0.34
FOLH1 Q04609 2/20 0.34
NAALAD2 Q9Y3Q0 2/20 0.34
ENPEP Q07075 2/20 0.34
CPA1 P15085 1/20 0.32
LTA4H P09960 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15905729 0.79 APAF1 (0.41) GABRR1APAF1CYP1A2FOLH1NAALAD2
SCHEMBL17266187 0.73 APAF1 (0.38) GABRR1APAF1CYP1A2FOLH1NAALAD2
SCHEMBL21787520 0.73 APAF1 (0.38) GABRR1APAF1CYP1A2FOLH1NAALAD2
SCHEMBL28643146 0.72 ANPEP (0.37) CPA1CYP2D6CYP2C19
SCHEMBL27546706 0.72
SCHEMBL12228330 0.71 APAF1 (0.39) GABRR1APAF1CYP1A2FOLH1NAALAD2
SCHEMBL22034668 0.71 ADRB2 (0.39) GABRR1APAF1CYP1A2FOLH1NAALAD2
SCHEMBL11307127 0.71 APAF1 (0.36) GABRR1APAF1CYP1A2FOLH1NAALAD2
SCHEMBL904646 0.70 GABRR1 (0.50) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL2037660 0.70 GABRR1 (0.50) GABRR1CYP1A2FOLH1NAALAD2ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295711-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ELECTRICAL CHARACTERISTICS ILLUMINA, INC. (US) 2023-09-21 US disclosed
EP-4172365-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ELECTRICAL CHARACTERISTICS Illumina, Inc. (US) 2023-05-03 EP disclosed
CN-115843316-A Compositions and methods for sequencing using at least electrical properties 伊鲁米纳公司 2023-03-24 CN disclosed
WO-2022005868-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ELECTRICAL CHARACTERISTICS ILLUMINA, INC. (US) 2022-01-06 WO disclosed
US-20100069491-A1 LIPID-AMINO ACID CONJUGATES AND METHODS OF USE UNIVERSITY OF MASSACHUSETTS (US) 2010-03-18 US disclosed
US-7544714-B2 Lipid-amino acid conjugates and methods of use UNIVERSITY OF MASSACHUSETTS (US) 2009-06-09 US disclosed
CN-101068537-A Lipid-amino acid conjugates and methods of use thereof UNIV MASSACHUSETTS (US) 2007-11-07 CN disclosed
EP-1778210-A2 LIPID-AMINO ACID CONJUGATES AND METHODS OF USE University of Massachusetts (US) 2007-05-02 EP disclosed
WO-2006010153-A2 LIPID-AMINO ACID CONJUGATES AND METHODS OF USE UNIVERSITY OF MASSACHUSETTS (US) 2006-01-26 WO disclosed
US-20060014820-A1 Lipid-amino acid conjugates and methods of use NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014820-A1 Lipid-amino acid conjugates and methods of use SLC27A2, SLC27A1, FABP2 GABRR1 646/4885APAF1 3313/4885CYP1A2 1210/4885
US-20100069491-A1 LIPID-AMINO ACID CONJUGATES AND METHODS OF USE SLC27A2, SLC27A1, FABP2 GABRR1 646/4885APAF1 3313/4885CYP1A2 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.