Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787522 | 0.89 | ENPEP (0.38) | APPENPEPLMNASLC6A6CYP2C19 | |
| SCHEMBL12541378 | 0.84 | CA2 (0.36) | APPENPEPCA2ANPEPEPHX2 | |
| SCHEMBL10230690 | 0.83 | APP (0.34) | APPENPEPCA2ANPEPEPHX2 | |
| SCHEMBL8722424 | 0.83 | ANPEP (0.36) | CA2ANPEPERAP2MAOAMAOB | |
| SCHEMBL14861611 | 0.80 | APP (0.40) | APPENPEPCA2ANPEPEPHX2 | |
| SCHEMBL917453 | 0.80 | CA2 (0.46) | APPCA2ANPEPEPHX2ERAP2 | |
| SCHEMBL7919805 | 0.78 | CA2 (0.45) | APPCA2ANPEPEPHX2ERAP2 | |
| SCHEMBL918428 | 0.78 | KMT2A (0.38) | APPCA2ANPEPEPHX2ERAP2 | |
| SCHEMBL918439 | 0.78 | KMT2A (0.38) | APPCA2ANPEPEPHX2ERAP2 | |
| SCHEMBL918429 | 0.78 | KMT2A (0.38) | APPCA2ANPEPEPHX2ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246344-A1 | Biological buffers with wide buffering ranges | DALY THOMAS (US) | 2021-08-12 | — | — | US | disclosed |
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | APP 2720/4885ENPEP 1044/4885CA2 43/4885 |
| US-20210246344-A1 | Biological buffers with wide buffering ranges | PEF1, SLC7A1, PLPBP | APP 2763/4885ENPEP 1085/4885CA2 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.