Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787523 | 0.89 | APP (0.36) | ENPEPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL12541389 | 0.83 | APAF1 (0.36) | ENPEPCYP2C19CYP2D6 | |
| SCHEMBL1553508 | 0.79 | PTGS1 (0.36) | ENPEPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL8722424 | 0.78 | ANPEP (0.36) | CYP2C19CYP2D6 | |
| SCHEMBL9117380 | 0.78 | CA2 (0.38) | LMNASLC6A6CYP2C19BLMCYP2D6 | |
| SCHEMBL21787524 | 0.77 | ANPEP (0.37) | LMNACYP2C19BLMCYP2D6 | |
| SCHEMBL11147726 | 0.76 | KMT2A (0.34) | LMNASLC6A6CYP2C19BLMCYP2D6 | |
| SCHEMBL28038412 | 0.75 | KMT2A (0.33) | LMNASLC6A6CYP2C19BLMCYP2D6 | |
| SCHEMBL7200678 | 0.73 | ENPEP (0.36) | ENPEPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL12541378 | 0.73 | CA2 (0.36) | ENPEPBLMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246344-A1 | Biological buffers with wide buffering ranges | DALY THOMAS (US) | 2021-08-12 | — | — | US | disclosed |
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | ENPEP 1044/4885LMNA 1639/4885SLC6A6 86/4885 |
| US-20210246344-A1 | Biological buffers with wide buffering ranges | PEF1, SLC7A1, PLPBP | ENPEP 1085/4885LMNA 1653/4885SLC6A6 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.