Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788050 | 0.76 | BRD4 (0.48) | BRD4ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL27261858 | 0.70 | ERN1 (0.38) | TYRERN1ALDH1A1KDM4EGAA | |
| SCHEMBL21787800 | 0.69 | BRD4 (0.68) | BRD4LMNAGLAHPGDSMN1; SMN2 | |
| SCHEMBL21776776 | 0.66 | BRD4 (0.67) | BRD4ALDH1A1HPGDMEN1MAPT | |
| SCHEMBL822908 | 0.63 | ESR1 (0.80) | TYRALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL24006927 | 0.63 | BRD4 (0.63) | BRD4POLB | |
| SCHEMBL21787802 | 0.63 | TAS1R3 (0.44) | ALDH1A1GAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL2681029 | 0.63 | CYP2A6 (0.70) | TYRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL17399576 | 0.62 | TYR (0.69) | TYRERN1KDM4EMEN1POLB | |
| P-Cymene SCHEMBL28761802 | 0.61 | TRIM24 (0.60) | TYRERN1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |