SCHEMBL822908

SCHEMBL822908

Cc1ccc(C(C)c2ccc(O)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.80
ESR2 Q92731 6/20 0.80
PDCD1 Q15116 1/20 0.80
CD274 Q9NZQ7 1/20 0.80
ACHE P22303 3/20 0.65
MAPT P10636 3/20 0.44
ALOX15 P16050 3/20 0.44
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP1A2 P05177 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
DRD1 P21728 1/20 0.44
TBXA2R P21731 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26946 0.89 ESR1 (1.00) ESR1ESR2PDCD1CD274ACHE
SCHEMBL10593295 0.89 ESR1 (1.00) ESR1ESR2PDCD1CD274ACHE
SCHEMBL14158781 0.88 ESR1 (0.61) ESR1ESR2PDCD1CD274ACHE
Methane SCHEMBL21952131 0.87 ESR1 (0.94) ESR1ESR2PDCD1CD274ACHE
Ammonia Solution, Strong SCHEMBL7989093 0.87 ESR1 (0.94) ESR1ESR2PDCD1CD274ACHE
SCHEMBL146509 0.87 ESR1 (0.55) ESR1ESR2PDCD1CD274ACHE
Ammonia Solution, Strong SCHEMBL7995783 0.84 ESR1 (0.52) ESR1ESR2PDCD1CD274ACHE
SCHEMBL6563988 0.82 ESR1 (0.84) ESR1ESR2PDCD1CD274MAPT
SCHEMBL20763933 0.82 ACHE (0.68) ESR1ESR2PDCD1CD274ACHE
SCHEMBL735987 0.82 ACHE (0.68) ESR1ESR2PDCD1CD274ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3212614-B1 PROCESS FOR MAKING BENZOXAZINES CYTEC IND INC (US) 2019-05-01 EP disclosed
US-9880322-B2 Benzyl (meth)acrylate monomers suitable for microstructured optical films 3M INNOVATIVE PROPERTIES CO. (US) 2018-01-30 US disclosed
US-20170369679-A1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2017-12-28 US disclosed
US-9783655-B2 NOR-HALS compounds as flame retardants BASF SE (DE) 2017-10-10 US disclosed
US-20160229989-A1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2016-08-11 US disclosed
US-9360591-B2 Microstructured film comprising nanoparticles and monomer comprising alkylene oxide repeat units 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-07 US disclosed
US-20150284535-A1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2015-10-08 US disclosed
US-20150241599-A1 MICROSTRUCTURED FILM COMPRISING NANOPARTICLES AND MONOMER COMPRISING ALKYLENE OXIDE REPEAT UNITS 3M INNOVATIVE PROPERTIES COMPANY 2015-08-27 US disclosed
US-8877838-B2 Melamine phenylphosphinate flame retardant compositions BASF SE (DE) 2014-11-04 US disclosed
US-20140316032-A1 P-N-COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2014-10-23 US disclosed
EP-0468921-A1 Aqueous dispersions of slightly soluble UV absorbing agents CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-5009668-A Mixture of assistants and its use in the dyeing of synthetic fibre materials: acid ester of oxyalkylated phendl, nonionic surfactant and dye carrier CIBA-GEIGY CORPORATION (US) 1991-04-23 US disclosed
US-5009669-A Aqueous dispensions of 2-(2'-hydroxyphenyl)benzotriazoles CIBA-GEIGY CORPORATION (US) 1991-04-23 US disclosed
EP-0414631-A1 Auxiliary agent mixture and its use in dyeing polyester fibre materials CIBA-GEIGY AG (CH) 1991-02-27 EP disclosed
US-4950810-A Selective process for preparting 2,4- or 3,6-di-substituted phenol compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1990-08-21 US disclosed
EP-0382138-A1 Auxiliary mixture and its use in dyeing synthetic fibrous materials CIBA-GEIGY AG (CH) 1990-08-16 EP disclosed
EP-0345219-A1 Aqueous dispersions of 2-(2'-hydroxyphenyl) benzotriazoles CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed
EP-0335674-A2 Selective process for preparing 2,4- or 3,6-di-substituted phenol compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-10-04 EP disclosed
US-4564632-A Insecticidal and acaricidal agents and their use BAYER AKTIENGESELLSCHAFT (DE) 1986-01-14 US disclosed
US-4380671-A LEWIS ACID CATALYZED REACTION OF SULFUR DICHLORIDE AND ALKYLPHENOL MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1983-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369679-A1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS PFAS, NONO, PARG ESR1 4170/4885ESR2 3543/4885PDCD1 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.