Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789039 | 0.93 | MAPT (0.44) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL21777274 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL21777358 | 0.89 | MAPT (0.47) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL21777359 | 0.89 | MAPT (0.47) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL29460074 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL21777440 | 0.84 | PPARG (0.42) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL17407152 | 0.83 | OGT (0.57) | ALDH1A1MAPTPOLBNPSR1PKM | |
| SCHEMBL24002418 | 0.81 | MAPT (0.51) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL3493926 | 0.77 | CTSS (0.53) | ALDH1A1SMN1; SMN2TSHRCTSKCTSS | |
| SCHEMBL21789052 | 0.77 | TRPM8 (0.44) | ALDH1A1MAPTPOLBNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12582644-B2 | O-GlcNAc transferase inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-03-24 | — | — | US | disclosed |
| CN-116162085-B | O-GlcNAc transferase inhibitor and application thereof | 重庆医科大学 | 2024-10-01 | — | — | CN | disclosed |
| US-20210346367-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-11 | — | — | US | disclosed |
| WO-2020047251-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12582644-B2 | O-GlcNAc transferase inhibitors and uses thereof | OGA, OGT, OSTC | ALDH1A1 1506/4885MAPT 62/4885POLB 608/4885 |
| US-20210346367-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | OGT, OGA, UGGT1 | ALDH1A1 1594/4885MAPT 34/4885POLB 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.