Ornithine Aketoglutarate

Ornithine Aketoglutarate

SCHEMBL2178954

C=CC(N)=O.NCCCC(N)C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.64
NOS2 P35228 5/20 0.47
TSHR P16473 3/20 0.47
CYP2C19 P33261 2/20 0.47
CYP1A2 P05177 2/20 0.47
GLA P06280 1/20 0.47
NFKB1 P19838 1/20 0.47
APEX1 P27695 1/20 0.47
KMT2A Q03164 2/20 0.45
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
NOS1 P29475 5/20 0.44
NOS3 P29474 4/20 0.44
MEN1 O00255 1/20 0.44
DDAH1 O94760 3/20 0.44
ARG2 P78540 4/20 0.44
ARG1 P05089 3/20 0.44
CYP3A4 P08684 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornithine Aketoglutarate SCHEMBL6512486 0.98 GSR (0.62) GSRNOS2TSHRCYP2C19CYP1A2
Lysine SCHEMBL6561904 0.94 GSR (0.74) GSRNOS2TSHRCYP2C19CYP1A2
Lysine SCHEMBL27645682 0.94 GSR (0.74) GSRNOS2TSHRCYP2C19CYP1A2
Lysine SCHEMBL28112654 0.93 GSR (0.71) GSRNOS2TSHRCYP2C19CYP1A2
Lysine SCHEMBL28112652 0.93 GSR (0.71) GSRNOS2TSHRCYP2C19CYP1A2
Ornithine Aketoglutarate SCHEMBL6883619 0.90 GSR (0.53) GSRNOS2TSHRCYP2C19CYP1A2
Ornithine SCHEMBL3952790 0.86 GSR (0.78) GSRNOS2TSHRCYP2C19CYP1A2
D-Ornithine SCHEMBL28249208 0.86 GSR (0.78) GSRNOS2TSHRCYP2C19CYP1A2
Ornithine SCHEMBL15904598 0.86 GSR (0.78) GSRNOS2TSHRCYP2C19CYP1A2
Ornithine Aketoglutarate SCHEMBL15904596 0.86 GSR (0.78) GSRNOS2TSHRCYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912894-B2 Antimicrobial and antifouling conformal hydrogel coatings CORNELL UNIVERSITY (US) 2024-02-27 US claimed
US-20200172741-A1 ANTIMICROBIAL AND ANTIFOULING CONFORMAL HYDROGEL COATINGS CORNELL UNIVERSITY 2020-06-04 US claimed
WO-2011079380-A1 TRANSPARENT BACTERIAL CELLULOSE NANOCOMPOSITE HYDROGELS AXCELON BIOPOLYMERS CORPORATION (CA) 2011-07-07 WO claimed
US-11912894-B2 Antimicrobial and antifouling conformal hydrogel coatings CORNELL UNIVERSITY (US) 2024-02-27 US disclosed
WO-2023091955-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISEASES AND INJURIES OHIO STATE INNOVATION FOUNDATION (US) 2023-05-25 WO disclosed
US-20200172741-A1 ANTIMICROBIAL AND ANTIFOULING CONFORMAL HYDROGEL COATINGS CORNELL UNIVERSITY 2020-06-04 US disclosed
CN-106334463-B A kind of anti-pollution polyvinylidene fluoride hollow-fibre membrane and preparation method thereof 东华大学 2019-02-01 CN disclosed
CN-106334463-A Anti-pollution polyvinylidene fluoride hollow-fiber membrane and preparation method thereof 东华大学 2017-01-18 CN disclosed
US-20050129769-A1 Polymeric articles for carrying therapeutic agents ALNIS BIOSCIENCES, INC. 2005-06-16 US disclosed
WO-2005027873-A2 THERAPEUTIC AMINOGLYCOSIDE-CONTAINING HYDROGEL NANOPARTICLES ALNIS BIOSCIENCES, INC. (US) 2005-03-31 WO disclosed
US-20040126900-A1 High affinity peptide- containing nanoparticles ALNIS BIOSCIENCES INC. 2004-07-01 US disclosed
JP-2004137382-A WATER-ABSORBING COMPOSITION EHIME PREFECTURE 2004-05-13 JP disclosed
EP-1276507-A2 HIGH AFFINITY PEPTIDE-CONTAINING NANOPARTICLES Alnis Biosciences, Inc. (US) 2003-01-22 EP disclosed
WO-2001078786-A2 HIGH AFFINITY PEPTIDE-CONTAINING NANOPARTICLES ALNIS BIOSCIENCES, INC. (US) 2001-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050129769-A1 Polymeric articles for carrying therapeutic agents CD44, EPCAM, CLTB GSR 1597/4885NOS2 2399/4885TSHR 1664/4885
US-20040126900-A1 High affinity peptide- containing nanoparticles LNPEP, IAPP, ACP1 GSR 4378/4885NOS2 2434/4885TSHR 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.